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Covid-19 in pregnant women and babies: What pediatricians need to know

Beginning in late 2019, a novel coronavirus labeled SARS-CoV-2 spread around the world, affecting millions. The impact of the disease on patients and on health care delivery has been unprecedented. Here, we review what is currently known about the effects of the virus and its clinical condition, Cov...

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Autores principales: Rozycki, Henry J., Kotecha, Sailesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293440/
https://www.ncbi.nlm.nih.gov/pubmed/32709462
http://dx.doi.org/10.1016/j.prrv.2020.06.006
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author Rozycki, Henry J.
Kotecha, Sailesh
author_facet Rozycki, Henry J.
Kotecha, Sailesh
author_sort Rozycki, Henry J.
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description Beginning in late 2019, a novel coronavirus labeled SARS-CoV-2 spread around the world, affecting millions. The impact of the disease on patients and on health care delivery has been unprecedented. Here, we review what is currently known about the effects of the virus and its clinical condition, Covid-19 in areas of relevance to those providing care to neonates. While aspects of pregnancy, including higher expression of the cell receptor for the virus, ACE2, could put these women at higher risk, preliminary epidemiological information does not support this. Viral carriage prevalence based on universal screening show that rates vary from 13% in “hot spots” such as New York City, to 3% in areas with lower cases. Vertical transmission risks are unknown but 3.1% of 311 babies born to mothers with Covid-19 were positive within a week of birth. The clinical description of 26 neonates <30 days of age showed no deaths and only one requiring intensive care. Risks for breast-feeding and for milk banks are discussed.
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spelling pubmed-72934402020-06-14 Covid-19 in pregnant women and babies: What pediatricians need to know Rozycki, Henry J. Kotecha, Sailesh Paediatr Respir Rev Review Beginning in late 2019, a novel coronavirus labeled SARS-CoV-2 spread around the world, affecting millions. The impact of the disease on patients and on health care delivery has been unprecedented. Here, we review what is currently known about the effects of the virus and its clinical condition, Covid-19 in areas of relevance to those providing care to neonates. While aspects of pregnancy, including higher expression of the cell receptor for the virus, ACE2, could put these women at higher risk, preliminary epidemiological information does not support this. Viral carriage prevalence based on universal screening show that rates vary from 13% in “hot spots” such as New York City, to 3% in areas with lower cases. Vertical transmission risks are unknown but 3.1% of 311 babies born to mothers with Covid-19 were positive within a week of birth. The clinical description of 26 neonates <30 days of age showed no deaths and only one requiring intensive care. Risks for breast-feeding and for milk banks are discussed. Elsevier Ltd. 2020-09 2020-06-13 /pmc/articles/PMC7293440/ /pubmed/32709462 http://dx.doi.org/10.1016/j.prrv.2020.06.006 Text en © 2020 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Review
Rozycki, Henry J.
Kotecha, Sailesh
Covid-19 in pregnant women and babies: What pediatricians need to know
title Covid-19 in pregnant women and babies: What pediatricians need to know
title_full Covid-19 in pregnant women and babies: What pediatricians need to know
title_fullStr Covid-19 in pregnant women and babies: What pediatricians need to know
title_full_unstemmed Covid-19 in pregnant women and babies: What pediatricians need to know
title_short Covid-19 in pregnant women and babies: What pediatricians need to know
title_sort covid-19 in pregnant women and babies: what pediatricians need to know
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293440/
https://www.ncbi.nlm.nih.gov/pubmed/32709462
http://dx.doi.org/10.1016/j.prrv.2020.06.006
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