Cargando…

Insights into SARS-CoV-2 genome, structure, evolution, pathogenesis and therapies: Structural genomics approach

The sudden emergence of severe respiratory disease, caused by a novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has recently become a public health emergency. Genome sequence analysis of SARS-CoV-2 revealed its close resemblance to the earlier reported SARS-CoV and Middle East re...

Descripción completa

Detalles Bibliográficos
Autores principales:	Naqvi, Ahmad Abu Turab, Fatima, Kisa, Mohammad, Taj, Fatima, Urooj, Singh, Indrakant K., Singh, Archana, Atif, Shaikh Muhammad, Hariprasad, Gururao, Hasan, Gulam Mustafa, Hassan, Md. Imtaiyaz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier B.V. 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293463/ https://www.ncbi.nlm.nih.gov/pubmed/32544429 http://dx.doi.org/10.1016/j.bbadis.2020.165878

Ejemplares similares

Insight into the Conformational Transitions of Serine Acetyl Transferase Isoforms in E. histolytica: Implications for Structural and Functional Balance
por: Idrees, Danish, et al.
Publicado: (2022)

Genomic Variations in the Structural Proteins of SARS-CoV-2 and Their Deleterious Impact on Pathogenesis: A Comparative Genomics Approach
por: Mohammad, Taj, et al.
Publicado: (2021)

Investigating host-virus interaction mechanism and phylogenetic analysis of viral proteins involved in the pathogenesis
por: Naqvi, Ahmad Abu Turab, et al.
Publicado: (2021)

Measuring Structural Changes in Cytochrome c under Crowded Conditions Using In Vitro and In Silico Approaches
por: Parray, Zahoor Ahmad, et al.
Publicado: (2022)

Identification of Functional Candidates amongst Hypothetical Proteins of Treponema pallidum ssp. pallidum
por: Naqvi, Ahmad Abu Turab, et al.
Publicado: (2015)

Correction: Identification of Functional Candidates amongst Hypothetical Proteins of Treponema pallidum ssp. pallidum
por: Naqvi, Ahmad Abu Turab, et al.
Publicado: (2018)

Structural genomics approach to investigate deleterious impact of nsSNPs in conserved telomere maintenance component 1
por: Choudhury, Arunabh, et al.
Publicado: (2021)

Structural Modeling of Wild and Mutant Forms of Human Plasma Platelet Activating Factor-Acetyl Hydrolase Enzyme
por: Khan, Mohd Imran, et al.
Publicado: (2020)

B Cell Lymphoma 2: A Potential Therapeutic Target for Cancer Therapy
por: Alam, Manzar, et al.
Publicado: (2021)

Structural and functional impact of non-synonymous SNPs in the CST complex subunit TEN1: structural genomics approach
por: Amir, Mohd., et al.
Publicado: (2019)

Molecular Modeling of Chemosensory Protein 3 from Spodoptera litura and Its Binding Property with Plant Defensive Metabolites
por: Singh, Sujata, et al.
Publicado: (2020)

Insights into the Conserved Regulatory Mechanisms of Human and Yeast Aging
por: Dahiya, Rashmi, et al.
Publicado: (2020)

Therapeutic Targeting of Regulated Signaling Pathways of Non-Small Cell Lung Carcinoma
por: Hasan, Gulam Mustafa, et al.
Publicado: (2023)

A Comprehensive Analysis of Calmodulin-Like Proteins of Glycine max Indicates Their Role in Calcium Signaling and Plant Defense Against Insect Attack
por: Yadav, Manisha, et al.
Publicado: (2022)

Discovery of Harmaline as a Potent Inhibitor of Sphingosine Kinase-1: A Chemopreventive Role in Lung Cancer
por: Roy, Sonam, et al.
Publicado: (2020)

Identification of Phytoconstituents as Potent Inhibitors of Casein Kinase-1 Alpha Using Virtual Screening and Molecular Dynamics Simulations
por: Shafie, Alaa, et al.
Publicado: (2021)

Investigating single amino acid substitutions in PIM1 kinase: A structural genomics approach
por: Shafie, Alaa, et al.
Publicado: (2021)

Sequence Analysis of Hypothetical Proteins from Helicobacter pylori 26695 to Identify Potential Virulence Factors
por: Naqvi, Ahmad Abu Turab, et al.
Publicado: (2016)

Analyzing the Effect of Vaccination Over COVID Cases and Deaths in Asian Countries Using Machine Learning Models
por: Rustagi, Vanshika, et al.
Publicado: (2022)

Green Composites Based on Animal Fiber and Their Applications for a Sustainable Future
por: Mann, Guravtar Singh, et al.
Publicado: (2023)

MARK4 Inhibited by AChE Inhibitors, Donepezil and Rivastigmine Tartrate: Insights into Alzheimer’s Disease Therapy
por: Shamsi, Anas, et al.
Publicado: (2020)

Comparative analysis of web-based programs for single amino acid substitutions in proteins
por: Choudhury, Arunabh, et al.
Publicado: (2022)

Biophysical Insights into Implications of PEG-400 on the α-Crystallin Structure: Multispectroscopic and Microscopic Approach
por: Shamsi, Anas, et al.
Publicado: (2020)

Structural modeling of Omicron spike protein and its complex with human ACE-2 receptor: Molecular basis for high transmissibility of the virus
por: Koley, Tirthankar, et al.
Publicado: (2022)

Comparative Structural Analysis of Human ACE2 Receptor with Spike Protein of SARS-CoV-2 Variants: Implications to Understand Infectivity of the Virus
por: Koley, Tirthankar, et al.
Publicado: (2022)

Identification of Sphingosine Kinase-1 Inhibitors from Bioactive Natural Products Targeting Cancer Therapy
por: Jairajpuri, Deeba Shamim, et al.
Publicado: (2020)

Identification of natural compounds as potent inhibitors of SARS-CoV-2 main protease using combined docking and molecular dynamics simulations
por: Jairajpuri, Deeba Shamim, et al.
Publicado: (2021)

Unraveling the Role of RNA Mediated Toxicity of C9orf72 Repeats in C9-FTD/ALS
por: Kumar, Vijay, et al.
Publicado: (2017)

Chemotherapy Resistance in Advanced Ovarian Cancer Patients
por: Pokhriyal, Ruchika, et al.
Publicado: (2019)

In-Silico Drug discovery approach targeting receptor tyrosine kinase-like orphan receptor 1 for cancer treatment
por: Nath, Onkar, et al.
Publicado: (2017)

Human Secretary Phospholipase A2 Mutations and Their Clinical Implications
por: Khan, Mohd Imran, et al.
Publicado: (2020)

Identification of intrinsically disorder regions in non-structural proteins of SARS-CoV-2: New insights into drug and vaccine resistance
por: Anjum, Farah, et al.
Publicado: (2022)

Discovery of Hordenine as a Potential Inhibitor of Pyruvate Dehydrogenase Kinase 3: Implication in Lung Cancer Therapy
por: Anwar, Saleha, et al.
Publicado: (2020)

Regulation of the regulators: Transcription factors controlling biosynthesis of plant secondary metabolites during biotic stresses and their regulation by miRNAs
por: Kajla, Mohini, et al.
Publicado: (2023)

Cooperative Unfolding of Residual Structure in Heat Denatured Proteins by Urea and Guanidinium Chloride
por: Singh, Ritu, et al.
Publicado: (2015)

Comprehensive Insights into Biological Roles of Rosmarinic Acid: Implications in Diabetes, Cancer and Neurodegenerative Diseases
por: Azhar, Md. Khabeer, et al.
Publicado: (2023)

Label-Free Proteomics of Oral Mucosa Tissue to Identify Potential Biomarkers That Can Flag Predilection of Precancerous Lesions to Oral Cell Carcinoma: A Preliminary Study
por: Sharma, Vipra, et al.
Publicado: (2023)

Potential drug targets of SARS-CoV-2: From genomics to therapeutics
por: Shamsi, Anas, et al.
Publicado: (2021)

Fight Hard or Die Trying: Current Status of Lipid Signaling during Plant–Pathogen Interaction
por: Mehta, Sahil, et al.
Publicado: (2021)

Natural products can be used in therapeutic management of COVID-19: Probable mechanistic insights
por: Ali, Sabeeha, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_tmqeeevnpfstaj8adaa0btqlbk