Development of child immunity in the context of COVID-19 pandemic

Children, because of having an immature immune system, are usually more prone than the adults to the microbial infections and have more severe symptoms, which is especially true for the newborns, and very young children. However, the review of clinical data from the current COVID-19 pandemic indicat...

Descripción completa

Detalles Bibliográficos
Autores principales: Kloc, Małgorzata, Ghobrial, Rafik M., Kuchar, Ernest, Lewicki, Sławomir, Kubiak, Jacek Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293525/
https://www.ncbi.nlm.nih.gov/pubmed/32544611
http://dx.doi.org/10.1016/j.clim.2020.108510
_version_ 1783546325440135168
author Kloc, Małgorzata
Ghobrial, Rafik M.
Kuchar, Ernest
Lewicki, Sławomir
Kubiak, Jacek Z.
author_facet Kloc, Małgorzata
Ghobrial, Rafik M.
Kuchar, Ernest
Lewicki, Sławomir
Kubiak, Jacek Z.
author_sort Kloc, Małgorzata
collection PubMed
description Children, because of having an immature immune system, are usually more prone than the adults to the microbial infections and have more severe symptoms, which is especially true for the newborns, and very young children. However, the review of clinical data from the current COVID-19 pandemic indicates otherwise. We discuss here what are the main features and components of children's immune system, the role of maternal transmission of immunity, and what are the possible explanations for the seemingly lower infection rate and severity of COVI-19 in children.
format Online
Article
Text
id pubmed-7293525
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Elsevier Inc.
record_format MEDLINE/PubMed
spelling pubmed-72935252020-06-14 Development of child immunity in the context of COVID-19 pandemic Kloc, Małgorzata Ghobrial, Rafik M. Kuchar, Ernest Lewicki, Sławomir Kubiak, Jacek Z. Clin Immunol Article Children, because of having an immature immune system, are usually more prone than the adults to the microbial infections and have more severe symptoms, which is especially true for the newborns, and very young children. However, the review of clinical data from the current COVID-19 pandemic indicates otherwise. We discuss here what are the main features and components of children's immune system, the role of maternal transmission of immunity, and what are the possible explanations for the seemingly lower infection rate and severity of COVI-19 in children. Elsevier Inc. 2020-08 2020-06-13 /pmc/articles/PMC7293525/ /pubmed/32544611 http://dx.doi.org/10.1016/j.clim.2020.108510 Text en © 2020 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Kloc, Małgorzata
Ghobrial, Rafik M.
Kuchar, Ernest
Lewicki, Sławomir
Kubiak, Jacek Z.
Development of child immunity in the context of COVID-19 pandemic
title Development of child immunity in the context of COVID-19 pandemic
title_full Development of child immunity in the context of COVID-19 pandemic
title_fullStr Development of child immunity in the context of COVID-19 pandemic
title_full_unstemmed Development of child immunity in the context of COVID-19 pandemic
title_short Development of child immunity in the context of COVID-19 pandemic
title_sort development of child immunity in the context of covid-19 pandemic
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293525/
https://www.ncbi.nlm.nih.gov/pubmed/32544611
http://dx.doi.org/10.1016/j.clim.2020.108510
work_keys_str_mv AT klocmałgorzata developmentofchildimmunityinthecontextofcovid19pandemic
AT ghobrialrafikm developmentofchildimmunityinthecontextofcovid19pandemic
AT kucharernest developmentofchildimmunityinthecontextofcovid19pandemic
AT lewickisławomir developmentofchildimmunityinthecontextofcovid19pandemic
AT kubiakjacekz developmentofchildimmunityinthecontextofcovid19pandemic

Ejemplares similares