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High-dose methotrexate in ICU patients: a retrospective study

BACKGROUND: High-dose methotrexate (HD-MTX) is commonly used in the treatment of solid tumors and hematological malignancies. Severe toxicities are frequent, leading to organ dysfunction and death. Risk–benefit ratio of using HD-MTX in critically ill patients is unknown. This study aims to describe...

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Detalles Bibliográficos
Autores principales:	Valade, Sandrine, Mariotte, Eric, Azoulay, Elie, Darmon, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293713/ https://www.ncbi.nlm.nih.gov/pubmed/32535662 http://dx.doi.org/10.1186/s13613-020-00693-5

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