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ε2 allele and ε2-involved genotypes (ε2/ε2, ε2/ε3, and ε2/ε4) may confer the association of APOE genetic polymorphism with risks of nephropathy in type 2 diabetes: a meta-analysis
BACKGROUND: Diabetic nephropathy (DN) contributes to end-stage renal failure. Microvascular injury resulted from reactive oxygen species is implicated in the pathogenesis of DN. Genetic polymorphism of Apolipoprotein E (APOE) influences the antioxidative properties of the protein. The relationship o...
Autores principales: | Shi, Jikang, Cheng, Zhaorui, Qiu, Shuang, Cui, Heran, Gu, Yulu, Zhao, Qian, Ren, Yaxuan, Zhang, He, Sun, Helin, Liu, Yunkai, Li, Yong, Qiao, Yichun, Hu, Yueyang, Liu, Yawen, Cheng, Yi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293775/ https://www.ncbi.nlm.nih.gov/pubmed/32534589 http://dx.doi.org/10.1186/s12944-020-01307-6 |
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