Loss of AKR1C1 is a good prognostic factor in advanced NPC cases and increases chemosensitivity to cisplatin in NPC cells

Cisplatin resistance is one of the main obstacles in the treatment of advanced nasopharyngeal carcinoma (NPC). AKR1C1 is a member of the Aldo‐keto reductase superfamily (AKRs), which converts aldehydes and ketones to their corresponding alcohols and has been reported to be involved in chemotherapeut...

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Detalles Bibliográficos
Autores principales: Zhou, Chen, Shen, Guowen, Yang, Fan, Duan, Jingling, Wu, Zhen, Yang, Mingqing, Liu, Yi, Du, Xueli, Zhang, Xiaoling, Xiao, Shengjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294127/
https://www.ncbi.nlm.nih.gov/pubmed/32307891
http://dx.doi.org/10.1111/jcmm.15291

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