Pristimerin‐induced uveal melanoma cell death via inhibiting PI3K/Akt/FoxO3a signalling pathway

Uveal melanoma (UM) is a highly invasive intraocular malignancy with high mortality. Presently, there is no FDA‐approved standard for the treatment of metastatic UM. Pristimerin is a natural quinine methide triterpenoid compound with anti‐angiogenic, anti‐cancer and anti‐inflammatory activities. How...

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Detalles Bibliográficos
Autores principales: Yan, Fengxia, Liao, Rifang, Silva, Marta, Li, Shuai, Jiang, Yizhou, Peng, Tangming, Lazarovici, Philip, Zheng, Wenhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294164/
https://www.ncbi.nlm.nih.gov/pubmed/32347651
http://dx.doi.org/10.1111/jcmm.15249

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294164/
https://www.ncbi.nlm.nih.gov/pubmed/32347651
http://dx.doi.org/10.1111/jcmm.15249

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