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Pristimerin‐induced uveal melanoma cell death via inhibiting PI3K/Akt/FoxO3a signalling pathway
Uveal melanoma (UM) is a highly invasive intraocular malignancy with high mortality. Presently, there is no FDA‐approved standard for the treatment of metastatic UM. Pristimerin is a natural quinine methide triterpenoid compound with anti‐angiogenic, anti‐cancer and anti‐inflammatory activities. How...
Autores principales: | Yan, Fengxia, Liao, Rifang, Silva, Marta, Li, Shuai, Jiang, Yizhou, Peng, Tangming, Lazarovici, Philip, Zheng, Wenhua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294164/ https://www.ncbi.nlm.nih.gov/pubmed/32347651 http://dx.doi.org/10.1111/jcmm.15249 |
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