VSV-Displayed HIV-1 Envelope Identifies Broadly Neutralizing Antibodies Class-Switched to IgG and IgA

The HIV-1 envelope (Env) undergoes conformational changes during infection. Broadly neutralizing antibodies (bNAbs) are typically isolated by using soluble Env trimers, which do not capture all Env states. To address these limitations, we devised a vesicular stomatitis virus (VSV)-based probe to dis...

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Detalles Bibliográficos
Autores principales: Jia, Manxue, Liberatore, Rachel A., Guo, Yicheng, Chan, Kun-Wei, Pan, Ruimin, Lu, Hong, Waltari, Eric, Mittler, Eva, Chandran, Kartik, Finzi, Andrés, Kaufmann, Daniel E., Seaman, Michael S., Ho, David D., Shapiro, Lawrence, Sheng, Zizhang, Kong, Xiang-Peng, Bieniasz, Paul D., Wu, Xueling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294236/
https://www.ncbi.nlm.nih.gov/pubmed/32315598
http://dx.doi.org/10.1016/j.chom.2020.03.024

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