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Cancer prevention with aspirin in hereditary colorectal cancer (Lynch syndrome), 10-year follow-up and registry-based 20-year data in the CAPP2 study: a double-blind, randomised, placebo-controlled trial

BACKGROUND: Lynch syndrome is associated with an increased risk of colorectal cancer and with a broader spectrum of cancers, especially endometrial cancer. In 2011, our group reported long-term cancer outcomes (mean follow-up 55·7 months [SD 31·4]) for participants with Lynch syndrome enrolled into...

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Detalles Bibliográficos
Autores principales: Burn, John, Sheth, Harsh, Elliott, Faye, Reed, Lynn, Macrae, Finlay, Mecklin, Jukka-Pekka, Möslein, Gabriela, McRonald, Fiona E, Bertario, Lucio, Evans, D Gareth, Gerdes, Anne-Marie, Ho, Judy W C, Lindblom, Annika, Morrison, Patrick J, Rashbass, Jem, Ramesar, Raj, Seppälä, Toni, Thomas, Huw J W, Pylvänäinen, Kirsi, Borthwick, Gillian M, Mathers, John C, Bishop, D Timothy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294238/
https://www.ncbi.nlm.nih.gov/pubmed/32534647
http://dx.doi.org/10.1016/S0140-6736(20)30366-4