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Human Purkinje in silico model enables mechanistic investigations into automaticity and pro-arrhythmic abnormalities
Cardiac Purkinje cells (PCs) are implicated in lethal arrhythmias caused by cardiac diseases, mutations, and drug action. However, the pro-arrhythmic mechanisms in PCs are not entirely understood, particularly in humans, as most investigations are conducted in animals. The aims of this study are to...
Autores principales: | Trovato, Cristian, Passini, Elisa, Nagy, Norbert, Varró, András, Abi-Gerges, Najah, Severi, Stefano, Rodriguez, Blanca |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Academic Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294239/ https://www.ncbi.nlm.nih.gov/pubmed/32251669 http://dx.doi.org/10.1016/j.yjmcc.2020.04.001 |
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