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CD137 Signaling Promotes Endothelial Apoptosis by Inhibiting Nrf2 Pathway, and Upregulating NF-κB Pathway

BACKGROUND: Endothelial dysfunction and apoptosis resulting from oxidative stress can lead to the development of atherosclerosis. Our group has previously showed that CD137 signaling contributes to the progression of atherosclerosis and the vulnerability of plaques. The aim of this study is to inves...

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Detalles Bibliográficos
Autores principales: Geng, Tianxin, Yan, Yang, Zhang, Yue, Xu, Liangjie, Zang, Guangyao, Yan, Jin Chuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294359/
https://www.ncbi.nlm.nih.gov/pubmed/32587470
http://dx.doi.org/10.1155/2020/4321912