Cargando…

CD137 Signaling Promotes Endothelial Apoptosis by Inhibiting Nrf2 Pathway, and Upregulating NF-κB Pathway

BACKGROUND: Endothelial dysfunction and apoptosis resulting from oxidative stress can lead to the development of atherosclerosis. Our group has previously showed that CD137 signaling contributes to the progression of atherosclerosis and the vulnerability of plaques. The aim of this study is to inves...

Descripción completa

Detalles Bibliográficos
Autores principales:	Geng, Tianxin, Yan, Yang, Zhang, Yue, Xu, Liangjie, Zang, Guangyao, Yan, Jin Chuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294359/ https://www.ncbi.nlm.nih.gov/pubmed/32587470 http://dx.doi.org/10.1155/2020/4321912

Ejemplares similares

Exosome derived from CD137‐modified endothelial cells regulates the Th17 responses in atherosclerosis
por: Xu, Liangjie, et al.
Publicado: (2020)

Contributions of Costimulatory Molecule CD137 in Endothelial Cells
por: Yuan, Wei, et al.
Publicado: (2021)

Visfatin induces the apoptosis of endothelial progenitor cells via the induction of pro-inflammatory mediators through the NF-κB pathway
por: Sun, Lina, et al.
Publicado: (2017)

CD137 Regulates NFATc1 Expression in Mouse VSMCs through TRAF6/NF-κB p65 Signaling Pathway
por: Yan, Jinchuan, et al.
Publicado: (2015)

CD137 agonist induces gastric cancer cell apoptosis by enhancing the functions of CD8(+) T cells via NF-κB signaling
por: Hu, Ben-Shun, et al.
Publicado: (2020)

Pomiferin Exerts Antineuroinflammatory Effects through Activating Akt/Nrf2 Pathway and Inhibiting NF-κB Pathway
por: Zhao, Yan, et al.
Publicado: (2022)

Effects of G-Rh2 on mast cell-mediated anaphylaxis via AKT-Nrf2/NF-κB and MAPK-Nrf2/NF-κB pathways
por: Xu, Chang, et al.
Publicado: (2022)

Dissecting the Crosstalk Between Nrf2 and NF-κB Response Pathways in Drug-Induced Toxicity
por: Gao, Wen, et al.
Publicado: (2022)

Geniposide suppressed OX-LDL-induced osteoblast apoptosis by regulating the NRF2/NF-κB signaling pathway
por: Xiao, Yaosheng, et al.
Publicado: (2023)

CD147 regulates extrinsic apoptosis in spermatocytes by modulating NFκB signaling pathways
por: Wang, Chaoqun, et al.
Publicado: (2016)

Macrophages enhance lipopolysaccharide induced apoptosis via Ang1 and NF-κB pathways in human umbilical vein endothelial cells
por: Cai, Guo-Long, et al.
Publicado: (2021)

Corynoline Alleviates Osteoarthritis Development via the Nrf2/NF-κB Pathway
por: Li, Sunlong, et al.
Publicado: (2022)

Activation of CD137 Signaling Promotes Angiogenesis in Atherosclerosis via Modulating Endothelial Smad1/5‐NFATc1 Pathway
por: Weng, Jiayi, et al.
Publicado: (2017)

Triptriolide Alleviates Lipopolysaccharide-Induced Liver Injury by Nrf2 and NF-κB Signaling Pathways
por: Yang, Yi-Qi, et al.
Publicado: (2018)

Pterostilbene reduces endothelial cell apoptosis by regulation of the Nrf2-mediated TLR-4/MyD88/NF-κB pathway in a rat model of atherosclerosis
por: Xiong, Xiaowei, et al.
Publicado: (2020)

VEGF promotes diabetic retinopathy by upregulating the PKC/ET/NF-κB/ICAM-1 signaling pathway
por: Zhang, Meiying, et al.
Publicado: (2022)

Silencing of PYGB suppresses growth and promotes the apoptosis of prostate cancer cells via the NF-κB/Nrf2 signaling pathway
por: Wang, Zhen, et al.
Publicado: (2018)

CD137-CD137 Ligand Interactions in Inflammation
por: Kwon, Byungsuk
Publicado: (2009)

Dissecting molecular cross-talk between Nrf2 and NF-κB response pathways
por: Wardyn, Joanna D., et al.
Publicado: (2015)

miR-137 targets the inhibition of TCF4 to reverse the progression of osteoarthritis through the AMPK/NF-κB signaling pathway
por: Wang, Jinyu, et al.
Publicado: (2020)

Nano hydroxyapatite induces glioma cell apoptosis by suppressing NF-κB signaling pathway
por: Guo, Guocai, et al.
Publicado: (2019)

Endothelial lipase is upregulated by interleukin-6 partly via the p38 MAPK and p65 NF-κB signaling pathways
por: Yue, Xin, et al.
Publicado: (2016)

MiR-590 Inhibits Endothelial Cell Apoptosis by Inactivating the TLR4/NF-κB Pathway in Atherosclerosis
por: Yang, Lei, et al.
Publicado: (2019)

CD40-Mediated Activation of the NF-κB2 Pathway
por: Hostager, Bruce S., et al.
Publicado: (2013)

Geraniin attenuates LPS-induced acute lung injury via inhibiting NF-κB and activating Nrf2 signaling pathways
por: Zhu, Guangfa, et al.
Publicado: (2017)

Naringenin ameliorates myocardial injury in STZ-induced diabetic mice by reducing oxidative stress, inflammation and apoptosis via regulating the Nrf2 and NF-κB signaling pathways
por: He, Yongpeng, et al.
Publicado: (2022)

Differential Contribution of NF-κB Signaling Pathways to CD4(+) Memory T Cell Induced Activation of Endothelial Cells
por: Jeucken, Kim C. M., et al.
Publicado: (2022)

Potential therapeutic effects of the simultaneous targeting of the Nrf2 and NF-κB pathways in diabetic neuropathy()
por: Ganesh Yerra, Veera, et al.
Publicado: (2013)

S-Allylmercaptocysteine Targets Nrf2 in Osteoarthritis Treatment Through NOX4/NF-κB Pathway
por: Yang, Guang, et al.
Publicado: (2020)

Isovitexin Depresses Osteoarthritis Progression via the Nrf2/NF-κB Pathway: An in vitro Study
por: Hu, Xiaofen, et al.
Publicado: (2021)

Stevioside attenuates osteoarthritis via regulating Nrf2/HO-1/NF-κB pathway
por: Wu, Jia, et al.
Publicado: (2022)

Targeting Nrf2 and NF-κB Signaling Pathways in Cancer Prevention: The Role of Apple Phytochemicals
por: Gado, Francesca, et al.
Publicado: (2023)

Nutraceutical Effect of Resveratrol on the Mammary Gland: Focusing on the NF-κb /Nrf2 Signaling Pathways
por: Malik, Muhammad Umair Ul Hassan, et al.
Publicado: (2023)

Mangiferin Alleviates Ovalbumin-Induced Allergic Rhinitis via Nrf2/HO-1/NF-κB Signaling Pathways
por: Piao, Chun Hua, et al.
Publicado: (2020)

Potential regulatory role of the Nrf2/HMGB1/TLR4/NF-κB signaling pathway in lupus nephritis
por: Li, Shi-jie, et al.
Publicado: (2023)

MGP Promotes Colon Cancer Proliferation by Activating the NF-κB Pathway through Upregulation of the Calcium Signaling Pathway
por: Li, Xueqing, et al.
Publicado: (2020)

Eupatilin Suppresses OVA-Induced Asthma by Inhibiting NF-κB and MAPK and Activating Nrf2 Signaling Pathways in Mice
por: Bai, Donghui, et al.
Publicado: (2022)

TNF-α and RANKL promote osteoclastogenesis by upregulating RANK via the NF-κB pathway
por: Luo, Gang, et al.
Publicado: (2018)

Lipid Peroxidation-Mediated Inflammation Promotes Cell Apoptosis through Activation of NF-κB Pathway in Rheumatoid Arthritis Synovial Cells
por: Yin, Geng, et al.
Publicado: (2015)

Paeonol-mediated apoptosis of hepatocellular carcinoma cells by NF-κB pathway
por: Li, Qiang, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_99v4mj8td50f22njnjjefkobdk