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Surface Display Technology for Biosensor Applications: A Review
Surface display is a recombinant technology that expresses target proteins on cell membranes and can be applied to almost all types of biological entities from viruses to mammalian cells. This technique has been used for various biotechnical and biomedical applications such as drug screening, biocat...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294428/ https://www.ncbi.nlm.nih.gov/pubmed/32414189 http://dx.doi.org/10.3390/s20102775 |
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author | Park, Min |
author_facet | Park, Min |
author_sort | Park, Min |
collection | PubMed |
description | Surface display is a recombinant technology that expresses target proteins on cell membranes and can be applied to almost all types of biological entities from viruses to mammalian cells. This technique has been used for various biotechnical and biomedical applications such as drug screening, biocatalysts, library screening, quantitative assays, and biosensors. In this review, the use of surface display technology in biosensor applications is discussed. In detail, phage display, bacterial surface display of Gram-negative and Gram-positive bacteria, and eukaryotic yeast cell surface display systems are presented. The review describes the advantages of surface display systems for biosensor applications and summarizes the applications of surface displays to biosensors. |
format | Online Article Text |
id | pubmed-7294428 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-72944282020-08-13 Surface Display Technology for Biosensor Applications: A Review Park, Min Sensors (Basel) Review Surface display is a recombinant technology that expresses target proteins on cell membranes and can be applied to almost all types of biological entities from viruses to mammalian cells. This technique has been used for various biotechnical and biomedical applications such as drug screening, biocatalysts, library screening, quantitative assays, and biosensors. In this review, the use of surface display technology in biosensor applications is discussed. In detail, phage display, bacterial surface display of Gram-negative and Gram-positive bacteria, and eukaryotic yeast cell surface display systems are presented. The review describes the advantages of surface display systems for biosensor applications and summarizes the applications of surface displays to biosensors. MDPI 2020-05-13 /pmc/articles/PMC7294428/ /pubmed/32414189 http://dx.doi.org/10.3390/s20102775 Text en © 2020 by the author. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Park, Min Surface Display Technology for Biosensor Applications: A Review |
title | Surface Display Technology for Biosensor Applications: A Review |
title_full | Surface Display Technology for Biosensor Applications: A Review |
title_fullStr | Surface Display Technology for Biosensor Applications: A Review |
title_full_unstemmed | Surface Display Technology for Biosensor Applications: A Review |
title_short | Surface Display Technology for Biosensor Applications: A Review |
title_sort | surface display technology for biosensor applications: a review |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294428/ https://www.ncbi.nlm.nih.gov/pubmed/32414189 http://dx.doi.org/10.3390/s20102775 |
work_keys_str_mv | AT parkmin surfacedisplaytechnologyforbiosensorapplicationsareview |