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Orexin A alleviates neuroinflammation via OXR2/CaMKKβ/AMPK signaling pathway after ICH in mice

BACKGROUND: Orexins are two neuropeptides (orexin A, OXA; orexin B, OXB) secreted mainly from the lateral hypothalamus, which exert a wide range of physiological effects by activating two types of receptors (orexin receptor 1, OXR1; orexin receptor 2, OXR2). OXA has equal affinity for OXR1 and OXR2,...

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Detalles Bibliográficos
Autores principales:	Li, Tao, Xu, Weilin, Ouyang, Jinsong, Lu, Xiaoyang, Sherchan, Prativa, Lenahan, Cameron, Irio, Giselle, Zhang, John H., Zhao, Jianhua, Zhang, Yongfa, Tang, Jiping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294616/ https://www.ncbi.nlm.nih.gov/pubmed/32539736 http://dx.doi.org/10.1186/s12974-020-01841-1

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