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Hypoxia-induced alternative splicing: the 11th Hallmark of Cancer

Hypoxia-induced alternative splicing is a potent driving force in tumour pathogenesis and progression. In this review, we update currents concepts of hypoxia-induced alternative splicing and how it influences tumour biology. Following brief descriptions of tumour-associated hypoxia and the pre-mRNA...

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Detalles Bibliográficos
Autores principales: Farina, Antonietta Rosella, Cappabianca, Lucia, Sebastiano, Michela, Zelli, Veronica, Guadagni, Stefano, Mackay, Andrew Reay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294618/
https://www.ncbi.nlm.nih.gov/pubmed/32536347
http://dx.doi.org/10.1186/s13046-020-01616-9