The predictive value of red cell distribution width for stroke severity and outcome

OBJECTIVES: In the present study, we sought to investigate the association between red cell distribution width (RDW) and stroke severity and outcome in patients who underwent anti-thrombolytic therapy with tissue plasminogen activator (tPA). RESULTS: In this prospective study, 282 stroke patients wh...

Descripción completa

Detalles Bibliográficos
Autores principales: Shahsavarinia, Kavous, Ghavam Laleh, Younes, Moharramzadeh, Payman, Pouraghaei, Mahboob, Sadeghi-Hokmabadi, Elyar, Seifar, Fatemeh, Hajibonabi, Farid, Khamnian, Zhila, Farhoudi, Mehdi, Mafi, Sara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294627/
https://www.ncbi.nlm.nih.gov/pubmed/32539809
http://dx.doi.org/10.1186/s13104-020-05125-y
_version_ 1783546519189716992
author Shahsavarinia, Kavous
Ghavam Laleh, Younes
Moharramzadeh, Payman
Pouraghaei, Mahboob
Sadeghi-Hokmabadi, Elyar
Seifar, Fatemeh
Hajibonabi, Farid
Khamnian, Zhila
Farhoudi, Mehdi
Mafi, Sara
author_facet Shahsavarinia, Kavous
Ghavam Laleh, Younes
Moharramzadeh, Payman
Pouraghaei, Mahboob
Sadeghi-Hokmabadi, Elyar
Seifar, Fatemeh
Hajibonabi, Farid
Khamnian, Zhila
Farhoudi, Mehdi
Mafi, Sara
author_sort Shahsavarinia, Kavous
collection PubMed
description OBJECTIVES: In the present study, we sought to investigate the association between red cell distribution width (RDW) and stroke severity and outcome in patients who underwent anti-thrombolytic therapy with tissue plasminogen activator (tPA). RESULTS: In this prospective study, 282 stroke patients who underwent tPA injection were included. The categorization of RDW to < 12.9% and > 13% values revealed insignificant difference in stroke severity score, accounting for the mean 36-h NIHSS of 8.19 ± 8.2 in normal RDW values and 9.94 ± 8.28in higher RDW group (p = 0.64). In seventh day, NIHSS was 6.46 ± 7.28 in normal RDW group and was 8.52 ± 8.35 in increased RDW group (p = 0.058). Neither the 36-h, nor the seventh day and 3-month mRS demonstrated significant difference between those with normal and higher RDW values.
format Online
Article
Text
id pubmed-7294627
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-72946272020-06-16 The predictive value of red cell distribution width for stroke severity and outcome Shahsavarinia, Kavous Ghavam Laleh, Younes Moharramzadeh, Payman Pouraghaei, Mahboob Sadeghi-Hokmabadi, Elyar Seifar, Fatemeh Hajibonabi, Farid Khamnian, Zhila Farhoudi, Mehdi Mafi, Sara BMC Res Notes Research Note OBJECTIVES: In the present study, we sought to investigate the association between red cell distribution width (RDW) and stroke severity and outcome in patients who underwent anti-thrombolytic therapy with tissue plasminogen activator (tPA). RESULTS: In this prospective study, 282 stroke patients who underwent tPA injection were included. The categorization of RDW to < 12.9% and > 13% values revealed insignificant difference in stroke severity score, accounting for the mean 36-h NIHSS of 8.19 ± 8.2 in normal RDW values and 9.94 ± 8.28in higher RDW group (p = 0.64). In seventh day, NIHSS was 6.46 ± 7.28 in normal RDW group and was 8.52 ± 8.35 in increased RDW group (p = 0.058). Neither the 36-h, nor the seventh day and 3-month mRS demonstrated significant difference between those with normal and higher RDW values. BioMed Central 2020-06-15 /pmc/articles/PMC7294627/ /pubmed/32539809 http://dx.doi.org/10.1186/s13104-020-05125-y Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research Note
Shahsavarinia, Kavous
Ghavam Laleh, Younes
Moharramzadeh, Payman
Pouraghaei, Mahboob
Sadeghi-Hokmabadi, Elyar
Seifar, Fatemeh
Hajibonabi, Farid
Khamnian, Zhila
Farhoudi, Mehdi
Mafi, Sara
The predictive value of red cell distribution width for stroke severity and outcome
title The predictive value of red cell distribution width for stroke severity and outcome
title_full The predictive value of red cell distribution width for stroke severity and outcome
title_fullStr The predictive value of red cell distribution width for stroke severity and outcome
title_full_unstemmed The predictive value of red cell distribution width for stroke severity and outcome
title_short The predictive value of red cell distribution width for stroke severity and outcome
title_sort predictive value of red cell distribution width for stroke severity and outcome
topic Research Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294627/
https://www.ncbi.nlm.nih.gov/pubmed/32539809
http://dx.doi.org/10.1186/s13104-020-05125-y
work_keys_str_mv AT shahsavariniakavous thepredictivevalueofredcelldistributionwidthforstrokeseverityandoutcome
AT ghavamlalehyounes thepredictivevalueofredcelldistributionwidthforstrokeseverityandoutcome
AT moharramzadehpayman thepredictivevalueofredcelldistributionwidthforstrokeseverityandoutcome
AT pouraghaeimahboob thepredictivevalueofredcelldistributionwidthforstrokeseverityandoutcome
AT sadeghihokmabadielyar thepredictivevalueofredcelldistributionwidthforstrokeseverityandoutcome
AT seifarfatemeh thepredictivevalueofredcelldistributionwidthforstrokeseverityandoutcome
AT hajibonabifarid thepredictivevalueofredcelldistributionwidthforstrokeseverityandoutcome
AT khamnianzhila thepredictivevalueofredcelldistributionwidthforstrokeseverityandoutcome
AT farhoudimehdi thepredictivevalueofredcelldistributionwidthforstrokeseverityandoutcome
AT mafisara thepredictivevalueofredcelldistributionwidthforstrokeseverityandoutcome
AT shahsavariniakavous predictivevalueofredcelldistributionwidthforstrokeseverityandoutcome
AT ghavamlalehyounes predictivevalueofredcelldistributionwidthforstrokeseverityandoutcome
AT moharramzadehpayman predictivevalueofredcelldistributionwidthforstrokeseverityandoutcome
AT pouraghaeimahboob predictivevalueofredcelldistributionwidthforstrokeseverityandoutcome
AT sadeghihokmabadielyar predictivevalueofredcelldistributionwidthforstrokeseverityandoutcome
AT seifarfatemeh predictivevalueofredcelldistributionwidthforstrokeseverityandoutcome
AT hajibonabifarid predictivevalueofredcelldistributionwidthforstrokeseverityandoutcome
AT khamnianzhila predictivevalueofredcelldistributionwidthforstrokeseverityandoutcome
AT farhoudimehdi predictivevalueofredcelldistributionwidthforstrokeseverityandoutcome
AT mafisara predictivevalueofredcelldistributionwidthforstrokeseverityandoutcome

Ejemplares similares