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Caenorhabditis elegans Lipin 1 moderates the lifespan‐shortening effects of dietary glucose by maintaining ω‐6 polyunsaturated fatty acids

Excessive glucose causes various diseases and decreases lifespan by altering metabolic processes, but underlying mechanisms remain incompletely understood. Here, we show that Lipin 1/LPIN‐1, a phosphatidic acid phosphatase and a putative transcriptional coregulator, prevents life‐shortening effects...

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Detalles Bibliográficos
Autores principales:	Jung, Yoonji, Kwon, Sujeong, Ham, Seokjin, Lee, Dongyeop, Park, Hae‐Eun H., Yamaoka, Yasuyo, Jeong, Dae‐Eun, Artan, Murat, Altintas, Ozlem, Park, Sangsoon, Hwang, Wooseon, Lee, Yujin, Son, Heehwa G., An, Seon Woo A., Kim, Eun Ji E., Seo, Mihwa, Lee, Seung‐Jae V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294780/ https://www.ncbi.nlm.nih.gov/pubmed/32475074 http://dx.doi.org/10.1111/acel.13150

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