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Epigenome signatures landscaped by histone H3K9me3 are associated with the synaptic dysfunction in Alzheimer's disease

The pathogenesis of Alzheimer's disease (AD) and the commonest cause of dementia in the elderly remain incompletely understood. Recently, epigenetic modifications have been shown to play a potential role in neurodegeneration, but the specific involvement of epigenetic signatures landscaped by h...

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Detalles Bibliográficos
Autores principales: Lee, Min Young, Lee, Junghee, Hyeon, Seung Jae, Cho, Hyesun, Hwang, Yu Jin, Shin, Jong‐Yeon, McKee, Ann C., Kowall, Neil W., Kim, Jong‐Il, Stein, Thor D., Hwang, Daehee, Ryu, Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294781/
https://www.ncbi.nlm.nih.gov/pubmed/32419307
http://dx.doi.org/10.1111/acel.13153