Cu(I) Controls Conformational States in Human Atox1 Metallochaperone: An EPR and Multiscale Simulation Study

[Image: see text] Atox1 is a human copper metallochaperone that is responsible for transferring copper ions from the main human copper transporter, hCtr1, to ATP7A/B in the Golgi apparatus. Atox1 interacts with the Ctr1 C-terminal domain as a dimer, although it transfers the copper ions to ATP7A/B i...

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Detalles Bibliográficos
Autores principales: Perkal, Ortal, Qasem, Zena, Turgeman, Meital, Schwartz, Renana, Gevorkyan-Airapetov, Lada, Pavlin, Matic, Magistrato, Alessandra, Major, Dan Thomas, Ruthstein, Sharon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294806/
https://www.ncbi.nlm.nih.gov/pubmed/32396355
http://dx.doi.org/10.1021/acs.jpcb.0c01744

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294806/
https://www.ncbi.nlm.nih.gov/pubmed/32396355
http://dx.doi.org/10.1021/acs.jpcb.0c01744

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