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Exploiting Correlations between Protein Abundance and the Functional Status of saeRS and sarA To Identify Virulence Factors of Potential Importance in the Pathogenesis of Staphylococcus aureus Osteomyelitis

[Image: see text] We used a murine model of postsurgical osteomyelitis (OM) to evaluate the relative virulence of the Staphylococcus aureus strain LAC and five isogenic variants that differ in the functional status of saeRS and sarA relative to each other. LAC and a variant in which saeRS activity i...

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Detalles Bibliográficos
Autores principales: Ramirez, Aura M., Byrum, Stephanie D., Beenken, Karen E., Washam, Charity, Edmondson, Rick D., Mackintosh, Samuel G., Spencer, Horace J., Tackett, Alan J., Smeltzer, Mark S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294808/
https://www.ncbi.nlm.nih.gov/pubmed/31722523
http://dx.doi.org/10.1021/acsinfecdis.9b00291