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Exploiting Correlations between Protein Abundance and the Functional Status of saeRS and sarA To Identify Virulence Factors of Potential Importance in the Pathogenesis of Staphylococcus aureus Osteomyelitis
[Image: see text] We used a murine model of postsurgical osteomyelitis (OM) to evaluate the relative virulence of the Staphylococcus aureus strain LAC and five isogenic variants that differ in the functional status of saeRS and sarA relative to each other. LAC and a variant in which saeRS activity i...
Autores principales: | Ramirez, Aura M., Byrum, Stephanie D., Beenken, Karen E., Washam, Charity, Edmondson, Rick D., Mackintosh, Samuel G., Spencer, Horace J., Tackett, Alan J., Smeltzer, Mark S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2019
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294808/ https://www.ncbi.nlm.nih.gov/pubmed/31722523 http://dx.doi.org/10.1021/acsinfecdis.9b00291 |
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