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Characteristics of in peripheral blood of 70 hospitalized patients and 8 diarrhea patients with COVID-19

Objective: To analyze the blood test indicators of patients after infection of COVID-19 in Chongqing and analyze the clinical indicators of 8 patients with diarrhea. Materials and Methods: From January 26, 2019 to February 13, 2020, 70 patients diagnosed with 2019-nCoV according to the World Health...

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Autores principales: Wei, Xiao-Yu, Jing, Ding, Jia, Bei, Li, Qing, Zhou, Xia-Qia, Gong, Ming-Feng, Zou, Jing-Bo, Zhang, Qiang, Huang, Wen-Xiang, Tian, Wen-Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294916/
https://www.ncbi.nlm.nih.gov/pubmed/32547309
http://dx.doi.org/10.7150/ijms.45743
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author Wei, Xiao-Yu
Jing, Ding
Jia, Bei
Li, Qing
Zhou, Xia-Qia
Gong, Ming-Feng
Zou, Jing-Bo
Zhang, Qiang
Huang, Wen-Xiang
Tian, Wen-Guang
author_facet Wei, Xiao-Yu
Jing, Ding
Jia, Bei
Li, Qing
Zhou, Xia-Qia
Gong, Ming-Feng
Zou, Jing-Bo
Zhang, Qiang
Huang, Wen-Xiang
Tian, Wen-Guang
author_sort Wei, Xiao-Yu
collection PubMed
description Objective: To analyze the blood test indicators of patients after infection of COVID-19 in Chongqing and analyze the clinical indicators of 8 patients with diarrhea. Materials and Methods: From January 26, 2019 to February 13, 2020, 70 patients diagnosed with 2019-nCoV according to the World Health Organization interim guidance for NCP and divided into diarrhea and non-diarrhea groups. The laboratory tests liver and kidney function, blood routine, coagulation function, and immune status. Results: The study population included 70 hospitalized patients with confirmed CONV-2019. NCP patients (43males and 27 females) with a mean age of 48.57±17.80 (9~82) years and only 4.3% of patients have lung-related diseases. The positive rate of ESR, CRP, PT, IL6, lymphocyte count, GGT, Prealbumin and CD4 was more than 50%. We further analyzed the differences between 8 diarrhea patients and 62 non-diarrhea patients. Among these indicators, only Lymphocyte, CRP, Prealbumin and Cystatin C positive rate is more than 50%. Although there is no statistical difference in GGT, 100% of the 7 patients tested decreased. Conclusion: Our data recommended that the ESR, CRP, PT, IL6, lymphocyte count, GGT, prealbumin and CD4 have important value in the diagnosis of COVID-19, and the decrease of GGT may be an important indicator for judging the intestinal dysfunction of patients.
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spelling pubmed-72949162020-06-15 Characteristics of in peripheral blood of 70 hospitalized patients and 8 diarrhea patients with COVID-19 Wei, Xiao-Yu Jing, Ding Jia, Bei Li, Qing Zhou, Xia-Qia Gong, Ming-Feng Zou, Jing-Bo Zhang, Qiang Huang, Wen-Xiang Tian, Wen-Guang Int J Med Sci Research Paper Objective: To analyze the blood test indicators of patients after infection of COVID-19 in Chongqing and analyze the clinical indicators of 8 patients with diarrhea. Materials and Methods: From January 26, 2019 to February 13, 2020, 70 patients diagnosed with 2019-nCoV according to the World Health Organization interim guidance for NCP and divided into diarrhea and non-diarrhea groups. The laboratory tests liver and kidney function, blood routine, coagulation function, and immune status. Results: The study population included 70 hospitalized patients with confirmed CONV-2019. NCP patients (43males and 27 females) with a mean age of 48.57±17.80 (9~82) years and only 4.3% of patients have lung-related diseases. The positive rate of ESR, CRP, PT, IL6, lymphocyte count, GGT, Prealbumin and CD4 was more than 50%. We further analyzed the differences between 8 diarrhea patients and 62 non-diarrhea patients. Among these indicators, only Lymphocyte, CRP, Prealbumin and Cystatin C positive rate is more than 50%. Although there is no statistical difference in GGT, 100% of the 7 patients tested decreased. Conclusion: Our data recommended that the ESR, CRP, PT, IL6, lymphocyte count, GGT, prealbumin and CD4 have important value in the diagnosis of COVID-19, and the decrease of GGT may be an important indicator for judging the intestinal dysfunction of patients. Ivyspring International Publisher 2020-05-17 /pmc/articles/PMC7294916/ /pubmed/32547309 http://dx.doi.org/10.7150/ijms.45743 Text en © The author(s) This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/). See http://ivyspring.com/terms for full terms and conditions.
spellingShingle Research Paper
Wei, Xiao-Yu
Jing, Ding
Jia, Bei
Li, Qing
Zhou, Xia-Qia
Gong, Ming-Feng
Zou, Jing-Bo
Zhang, Qiang
Huang, Wen-Xiang
Tian, Wen-Guang
Characteristics of in peripheral blood of 70 hospitalized patients and 8 diarrhea patients with COVID-19
title Characteristics of in peripheral blood of 70 hospitalized patients and 8 diarrhea patients with COVID-19
title_full Characteristics of in peripheral blood of 70 hospitalized patients and 8 diarrhea patients with COVID-19
title_fullStr Characteristics of in peripheral blood of 70 hospitalized patients and 8 diarrhea patients with COVID-19
title_full_unstemmed Characteristics of in peripheral blood of 70 hospitalized patients and 8 diarrhea patients with COVID-19
title_short Characteristics of in peripheral blood of 70 hospitalized patients and 8 diarrhea patients with COVID-19
title_sort characteristics of in peripheral blood of 70 hospitalized patients and 8 diarrhea patients with covid-19
topic Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294916/
https://www.ncbi.nlm.nih.gov/pubmed/32547309
http://dx.doi.org/10.7150/ijms.45743
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