Cargando…
Targeting ERα degradation by L-Tetrahydropalmatine provides a novel strategy for breast cancer treatment
The incidence and mortality of breast cancer (BCa) are the highest among female cancers. There are approximate 70% BCa that are classified as estrogen receptor alpha (ERα) positive. Therefore, targeting ERα is the most significantly therapeutic schedule. However, patients with breast cancer develop...
Autores principales: | Xia, Xiaohong, He, Jinchan, Liu, Bin, Shao, Zhenlong, Xu, Qiong, Hu, Tumei, Yu, Cuifu, Liu, Xiaolin, Liao, Yuning, Liu, Ningning, Huang, Hongbiao |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294940/ https://www.ncbi.nlm.nih.gov/pubmed/32549765 http://dx.doi.org/10.7150/ijbs.44005 |
Ejemplares similares
-
USP10 deletion inhibits macrophage-derived foam cell formation and cellular-oxidized low density lipoprotein uptake by promoting the degradation of CD36
por: Xia, Xiaohong, et al.
Publicado: (2020) -
The deubiquitinating enzyme USP15 stabilizes ERα and promotes breast cancer progression
por: Xia, Xiaohong, et al.
Publicado: (2021) -
Selective degradation of AR-V7 to overcome castration resistance of prostate cancer
por: Liu, Yuan, et al.
Publicado: (2021) -
Deubiquitination of CD36 by UCHL1 promotes foam cell formation
por: Xia, Xiaohong, et al.
Publicado: (2020) -
Neddylation of HER2 Inhibits its Protein Degradation and promotes Breast Cancer Progression
por: Xia, Xiaohong, et al.
Publicado: (2023)