SETDB2 promoted breast cancer stem cell maintenance by interaction with and stabilization of ΔNp63α protein

The histone H3K9 methyltransferase SETDB2 is involved in cell cycle dysregulation in acute leukemia and has oncogenic roles in gastric cancer. In our study, we found that SETDB2 plays essential roles in breast cancer stem cell maintenance. Depleted SETDB2 significantly decreased the breast cancer st...

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Detalles Bibliográficos
Autores principales: Ying, Liu, Fei, Xie, Jialun, Li, Jianpeng, Xiao, Jie, Wang, Zhaolin, Mei, Hongjia, Fan, Huan, Fang, Sha, Li, Qiuju, Wu, Lin, Yuan, Cuicui, Liu, You, Peng, Weiwei, Zhao, Lulu, Wang, Jiemin, Wong, Jing, Li, Jing, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294945/
https://www.ncbi.nlm.nih.gov/pubmed/32549764
http://dx.doi.org/10.7150/ijbs.43611

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