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Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant

Altered serotonin (5-HT) signaling is associated with multiple brain disorders, including major depressive disorder (MDD), obsessive-compulsive disorder (OCD), and autism spectrum disorder (ASD). The presynaptic, high-affinity 5-HT transporter (SERT) tightly regulates 5-HT clearance after release fr...

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Detalles Bibliográficos
Autores principales: Quinlan, Meagan A., Robson, Matthew J., Ye, Ran, Rose, Kristie L., Schey, Kevin L., Blakely, Randy D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295033/
https://www.ncbi.nlm.nih.gov/pubmed/32581705
http://dx.doi.org/10.3389/fnmol.2020.00089