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Preclinical evaluation of an (111)In/(225)Ac theranostic targeting transformed MUC1 for triple negative breast cancer

Rationale: Transformed MUC1 (tMUC1) is a cancer-associated antigen that is overexpressed in >90% of triple-negative breast cancers (TNBC), a highly metastatic and aggressive subtype of breast cancer. TAB004, a murine antibody targeting tMUC1, has shown efficacy for the targeted delivery of therap...

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Detalles Bibliográficos
Autores principales: Kelly, Vanessa J, Wu, Shu-Ta, Gottumukkala, Vijay, Coelho, Richard, Palmer, Keryn, Nair, Surabhi, Erick, Timothy, Puri, Rahul, Ilovich, Ohad, Mukherjee, Pinku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295045/
https://www.ncbi.nlm.nih.gov/pubmed/32550914
http://dx.doi.org/10.7150/thno.38236