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Stem cell-derived exosomes prevent pyroptosis and repair ischemic muscle injury through a novel exosome/circHIPK3/ FOXO3a pathway

Rational: Ischemic injury of the skeletal muscle remains a serious clinical problem and currently there is no effective therapy. The aim of the present study is to determine whether human umbilical cord mesenchymal stem cells- derived exosomes (UMSC-Exo) could repair ischemic injury by releasing cir...

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Detalles Bibliográficos
Autores principales: Yan, Bing, Zhang, Yu, Liang, Chun, Liu, Bin, Ding, Fengzhi, Wang, Yanli, Zhu, Bao, Zhao, Ranzun, Yu, Xi-Yong, Li, Yangxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295049/
https://www.ncbi.nlm.nih.gov/pubmed/32550900
http://dx.doi.org/10.7150/thno.42259