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Stem cell-derived exosomes prevent pyroptosis and repair ischemic muscle injury through a novel exosome/circHIPK3/ FOXO3a pathway
Rational: Ischemic injury of the skeletal muscle remains a serious clinical problem and currently there is no effective therapy. The aim of the present study is to determine whether human umbilical cord mesenchymal stem cells- derived exosomes (UMSC-Exo) could repair ischemic injury by releasing cir...
Autores principales: | Yan, Bing, Zhang, Yu, Liang, Chun, Liu, Bin, Ding, Fengzhi, Wang, Yanli, Zhu, Bao, Zhao, Ranzun, Yu, Xi-Yong, Li, Yangxin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295049/ https://www.ncbi.nlm.nih.gov/pubmed/32550900 http://dx.doi.org/10.7150/thno.42259 |
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