HDAC6-specific inhibitor suppresses Th17 cell function via the HIF-1α pathway in acute lung allograft rejection in mice

Background: Previous animal experiments and clinical studies indicated the critical role of Th17 cells in lung transplant rejection. Therefore, the downregulation of Th17 cell function in lung transplant recipients is of great interest. Methods: We established an orthotopic mouse lung transplantatio...

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Detalles Bibliográficos
Autores principales: Zhou, Wenyong, Yang, Jun, Saren, Gaowa, Zhao, Heng, Cao, Kejian, Fu, Shijie, Pan, Xufeng, Zhang, Huijun, Wang, An, Chen, Xiaofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295069/
https://www.ncbi.nlm.nih.gov/pubmed/32550904
http://dx.doi.org/10.7150/thno.44961

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