Whole-Genome and RNA Sequencing Reveal Variation and Transcriptomic Coordination in the Developing Human Prefrontal Cortex

Gene expression levels vary across developmental stage, cell type, and region in the brain. Genomic variants also contribute to the variation in expression, and some neuropsychiatric disorder loci may exert their effects through this mechanism. To investigate these relationships, we present BrainVar...

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Detalles Bibliográficos
Autores principales: Werling, Donna M., Pochareddy, Sirisha, Choi, Jinmyung, An, Joon-Yong, Sheppard, Brooke, Peng, Minshi, Li, Zhen, Dastmalchi, Claudia, Santpere, Gabriel, Sousa, André M.M., Tebbenkamp, Andrew T.N, Kaur, Navjot, Gulden, Forrest O., Breen, Michael S., Liang, Lindsay, Gilson, Michael C., Zhao, Xuefang, Dong, Shan, Klei, Lambertus, Cicek, A. Ercument, Buxbaum, Joseph D., Adle-Biassette, Homa, Thomas, Jean-Leon, Aldinger, Kimberly A., O’Day, Diana R., Glass, Ian A., Zaitlen, Noah A., Talkowski, Michael E., Roeder, Kathryn, State, Matthew W., Devlin, Bernie, Sanders, Stephan J., Sestan, Nenad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295160/
https://www.ncbi.nlm.nih.gov/pubmed/32268104
http://dx.doi.org/10.1016/j.celrep.2020.03.053

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