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Self-assembly of the bZIP transcription factor ΔFosB

ΔFosB is a highly stable transcription factor that accumulates in specific brain regions upon chronic exposure to drugs of abuse, stress, or seizures, and mediates lasting behavioral responses. ΔFosB reportedly heterodimerizes with JunD forming a canonical bZIP leucine zipper coiled coil that clamps...

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Detalles Bibliográficos
Autores principales: Yin, Zhou, Venkannagari, Harikanth, Lynch, Haley, Aglyamova, Galina, Bhandari, Mukund, Machius, Mischa, Nestler, Eric J., Robison, Alfred J., Rudenko, Gabby
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295165/
https://www.ncbi.nlm.nih.gov/pubmed/32542236
http://dx.doi.org/10.1016/j.crstbi.2019.12.001