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A de novo approach to inferring within-host fitness effects during untreated HIV-1 infection
In the absence of effective antiviral therapy, HIV-1 evolves in response to the within-host environment, of which the immune system is an important aspect. During the earliest stages of infection, this process of evolution is very rapid, driven by a small number of CTL escape mutations. As the infec...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295245/ https://www.ncbi.nlm.nih.gov/pubmed/32492061 http://dx.doi.org/10.1371/journal.ppat.1008171 |