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Targeting Tumorigenicity of Breast Cancer Stem Cells Using SAHA/Wnt-b Catenin Antagonist Loaded Onto Protein Corona of Gold Nanoparticles

BACKGROUND: Among various theories for the origin of cancer, the “stemness phenotype model” suggests a dynamic feature for tumor cells in which non-cancer stem cells (non-CSCs) can inter-convert to CSCs. Differentiation with histone-deacetylase inhibitor, vorinostat (SAHA), can induce stem cells to...

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Detalles Bibliográficos
Autores principales:	Shamsian, Azam, Sepand, Mohammad Reza, Javaheri Kachousangi, Marziye, Dara, Tahereh, Ostad, Seyed Nasser, Atyabi, Fatemeh, Ghahremani, Mohammad Hossein
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295335/ https://www.ncbi.nlm.nih.gov/pubmed/32606664 http://dx.doi.org/10.2147/IJN.S234636

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