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Rechallenge patients with immune checkpoint inhibitors following severe immune-related adverse events: review of the literature and suggested prophylactic strategy

Patients with cancer who developed severe, grade 3 or 4 immune-related adverse events (irAEs) during therapy with immune checkpoint inhibitors are at risk for developing severe toxicities again on rechallenge with checkpoint inhibitors. Consequently, medical oncologists and multidisciplinary teams a...

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Detalles Bibliográficos
Autores principales: Haanen, John, Ernstoff, Marc, Wang, Yinghong, Menzies, Alexander, Puzanov, Igor, Grivas, Petros, Larkin, James, Peters, Solange, Thompson, John, Obeid, Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295425/
https://www.ncbi.nlm.nih.gov/pubmed/32532839
http://dx.doi.org/10.1136/jitc-2020-000604