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Annexin-A1 promotes RIG-I-dependent signaling and apoptosis via regulation of the IRF3–IFNAR–STAT1–IFIT1 pathway in A549 lung epithelial cells

Within the last century, millions of lives have been lost to the four major Influenza pandemics. These influenza pandemics were all caused by Influenza Type A viruses (IAV) through their ability to undergo antigenic drifts and shifts. A greater understanding of IAV and host–pathogen interactions is...

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Detalles Bibliográficos
Autores principales: Yap, Gracemary L. R., Sachaphibulkij, Karishma, Foo, Sok Lin, Cui, Jianzhou, Fairhurst, Anna-Marie, Lim, Lina H. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295754/
https://www.ncbi.nlm.nih.gov/pubmed/32541772
http://dx.doi.org/10.1038/s41419-020-2625-7