A constricted opening in Kir channels does not impede potassium conduction

The canonical mechanistic model explaining potassium channel gating is of a conformational change that alternately dilates and constricts a collar-like intracellular entrance to the pore. It is based on the premise that K(+) ions maintain a complete hydration shell while passing between the transmem...

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Detalles Bibliográficos
Autores principales: Black, Katrina A., He, Sitong, Jin, Ruitao, Miller, David M., Bolla, Jani R., Clarke, Oliver B., Johnson, Paul, Windley, Monique, Burns, Christopher J., Hill, Adam P., Laver, Derek, Robinson, Carol V., Smith, Brian J., Gulbis, Jacqueline M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295778/
https://www.ncbi.nlm.nih.gov/pubmed/32541684
http://dx.doi.org/10.1038/s41467-020-16842-0

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