Atomic-resolution mapping of transcription factor-DNA interactions by femtosecond laser crosslinking and mass spectrometry

Transcription factors (TFs) regulate target genes by specific interactions with DNA sequences. Detecting and understanding these interactions at the molecular level is of fundamental importance in biological and clinical contexts. Crosslinking mass spectrometry is a powerful tool to assist the struc...

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Detalles Bibliográficos
Autores principales: Reim, Alexander, Ackermann, Roland, Font-Mateu, Jofre, Kammel, Robert, Beato, Miguel, Nolte, Stefan, Mann, Matthias, Russmann, Christoph, Wierer, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295792/
https://www.ncbi.nlm.nih.gov/pubmed/32541649
http://dx.doi.org/10.1038/s41467-020-16837-x

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