Conditional Knockout of PKC-δ in Osteoclasts Favors Bone Mass Accrual in Males Due to Decreased Osteoclast Function

Protein kinase C delta (PKC-δ) functions as an important regulator in bone metabolism. However, the precise involvement of PKC-δ in the regulation of osteoclasts remains elusive. We generated an osteoclast specific PKC-δ knockout mouse strain to investigate the function of PKC-δ in osteoclast biolog...

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Detalles Bibliográficos
Autores principales: Li, Shangfu, He, Tianwei, Wu, Depeng, Zhang, Liangming, Chen, Ruiqiang, Liu, Bin, Yuan, Jinbo, Tickner, Jennifer, Qin, An, Xu, Jiake, Rong, Limin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295979/
https://www.ncbi.nlm.nih.gov/pubmed/32582715
http://dx.doi.org/10.3389/fcell.2020.00450

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295979/
https://www.ncbi.nlm.nih.gov/pubmed/32582715
http://dx.doi.org/10.3389/fcell.2020.00450

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