USP42 enhances homologous recombination repair by promoting R-loop resolution with a DNA–RNA helicase DHX9

The nucleus of mammalian cells is compartmentalized by nuclear bodies such as nuclear speckles, however, involvement of nuclear bodies, especially nuclear speckles, in DNA repair has not been actively investigated. Here, our focused screen for nuclear speckle factors involved in homologous recombina...

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Detalles Bibliográficos
Autores principales: Matsui, Misaki, Sakasai, Ryo, Abe, Masako, Kimura, Yusuke, Kajita, Shoki, Torii, Wakana, Katsuki, Yoko, Ishiai, Masamichi, Iwabuchi, Kuniyoshi, Takata, Minoru, Nishi, Ryotaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296013/
https://www.ncbi.nlm.nih.gov/pubmed/32541651
http://dx.doi.org/10.1038/s41389-020-00244-4

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