Cargando…
Sialylation and Galectin-3 in Microglia-Mediated Neuroinflammation and Neurodegeneration
Microglia are brain macrophages that mediate neuroinflammation and contribute to and protect against neurodegeneration. The terminal sugar residue of all glycoproteins and glycolipids on the surface of mammalian cells is normally sialic acid, and addition of this negatively charged residue is known...
Autores principales: | Puigdellívol, Mar, Allendorf, David H., Brown, Guy C. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296093/ https://www.ncbi.nlm.nih.gov/pubmed/32581723 http://dx.doi.org/10.3389/fncel.2020.00162 |
Ejemplares similares
-
Activated microglia desialylate their surface, stimulating complement receptor 3‐mediated phagocytosis of neurons
por: Allendorf, David H., et al.
Publicado: (2019) -
Calreticulin and Galectin-3 Opsonise Bacteria for Phagocytosis by Microglia
por: Cockram, Tom O. J., et al.
Publicado: (2019) -
Microglia in Neuroinflammation and Neurodegeneration: From Understanding to Therapy
por: Muzio, Luca, et al.
Publicado: (2021) -
Activated Microglia Desialylate and Phagocytose Cells via Neuraminidase, Galectin-3, and Mer Tyrosine Kinase
por: Nomura, Koji, et al.
Publicado: (2017) -
Neu1 Is Released From Activated Microglia, Stimulating Microglial Phagocytosis and Sensitizing Neurons to Glutamate
por: Allendorf, David H., et al.
Publicado: (2022)