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Immune checkpoint blockade: releasing the breaks or a protective barrier to COVID-19 severe acute respiratory syndrome?

The rapid emergence of COVID-19 has sent shockwaves through healthcare systems globally, with cancer patients at increased risk. The interplay of the virus and host immune system has been implicated in the development of ARDS. Immunotherapy agents have the potential to adversely potentiate this phen...

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Autores principales: Pickles, Oliver J., Lee, Lennard Y. W., Starkey, Thomas, Freeman-Mills, Luke, Olsson-Brown, Anna, Cheng, Vinton, Hughes, Daniel J., Lee, Alvin, Purshouse, Karin, Middleton, Gary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296191/
https://www.ncbi.nlm.nih.gov/pubmed/32546835
http://dx.doi.org/10.1038/s41416-020-0930-7
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author Pickles, Oliver J.
Lee, Lennard Y. W.
Starkey, Thomas
Freeman-Mills, Luke
Olsson-Brown, Anna
Cheng, Vinton
Hughes, Daniel J.
Lee, Alvin
Purshouse, Karin
Middleton, Gary
author_facet Pickles, Oliver J.
Lee, Lennard Y. W.
Starkey, Thomas
Freeman-Mills, Luke
Olsson-Brown, Anna
Cheng, Vinton
Hughes, Daniel J.
Lee, Alvin
Purshouse, Karin
Middleton, Gary
author_sort Pickles, Oliver J.
collection PubMed
description The rapid emergence of COVID-19 has sent shockwaves through healthcare systems globally, with cancer patients at increased risk. The interplay of the virus and host immune system has been implicated in the development of ARDS. Immunotherapy agents have the potential to adversely potentiate this phenomenon, requiring careful real-world observation.
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spelling pubmed-72961912020-06-16 Immune checkpoint blockade: releasing the breaks or a protective barrier to COVID-19 severe acute respiratory syndrome? Pickles, Oliver J. Lee, Lennard Y. W. Starkey, Thomas Freeman-Mills, Luke Olsson-Brown, Anna Cheng, Vinton Hughes, Daniel J. Lee, Alvin Purshouse, Karin Middleton, Gary Br J Cancer Comment The rapid emergence of COVID-19 has sent shockwaves through healthcare systems globally, with cancer patients at increased risk. The interplay of the virus and host immune system has been implicated in the development of ARDS. Immunotherapy agents have the potential to adversely potentiate this phenomenon, requiring careful real-world observation. Nature Publishing Group UK 2020-06-16 2020-09-01 /pmc/articles/PMC7296191/ /pubmed/32546835 http://dx.doi.org/10.1038/s41416-020-0930-7 Text en © Cancer Research UK 2020 https://creativecommons.org/licenses/by/4.0/Note This work is published under the standard license to publish agreement. After 12 months the work will become freely available and the license terms will switch to a Creative Commons Attribution 4.0 International (CC BY 4.0).
spellingShingle Comment
Pickles, Oliver J.
Lee, Lennard Y. W.
Starkey, Thomas
Freeman-Mills, Luke
Olsson-Brown, Anna
Cheng, Vinton
Hughes, Daniel J.
Lee, Alvin
Purshouse, Karin
Middleton, Gary
Immune checkpoint blockade: releasing the breaks or a protective barrier to COVID-19 severe acute respiratory syndrome?
title Immune checkpoint blockade: releasing the breaks or a protective barrier to COVID-19 severe acute respiratory syndrome?
title_full Immune checkpoint blockade: releasing the breaks or a protective barrier to COVID-19 severe acute respiratory syndrome?
title_fullStr Immune checkpoint blockade: releasing the breaks or a protective barrier to COVID-19 severe acute respiratory syndrome?
title_full_unstemmed Immune checkpoint blockade: releasing the breaks or a protective barrier to COVID-19 severe acute respiratory syndrome?
title_short Immune checkpoint blockade: releasing the breaks or a protective barrier to COVID-19 severe acute respiratory syndrome?
title_sort immune checkpoint blockade: releasing the breaks or a protective barrier to covid-19 severe acute respiratory syndrome?
topic Comment
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296191/
https://www.ncbi.nlm.nih.gov/pubmed/32546835
http://dx.doi.org/10.1038/s41416-020-0930-7
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