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Synthesis, antiinflammatory activity, and molecular docking studies of bisphosphonic esters as potential MMP-8 and MMP-9 inhibitors

Bisphosphonic acids (or bisphosphonates) have been successfully used in the clinic treatment of bone diseases for over decades. Additionally, the antiinflammatory activity of these compounds has been gaining attention. In our previous work, we synthesized and in vivo evaluated the bisphosphonic este...

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Detalles Bibliográficos
Autores principales: Cortes-Pacheco, Abimelek, Jiménez-Arellanes, María Adelina, Palacios-Can, Francisco José, Valcarcel-Gamiño, José Antonio, Razo-Hernández, Rodrigo Said, Juárez-Vázquez, María del Carmen, López-Torres, Adolfo, Ramírez-Marroquín, Oscar Abelardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296197/
https://www.ncbi.nlm.nih.gov/pubmed/32566030
http://dx.doi.org/10.3762/bjoc.16.108