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Clinical characteristics and long-term prognosis of ischemic and non-ischemic cardiomyopathy

OBJECTIVES: The different etiology of HF has different prognostic risk factors. Prognosis assessment of ICM and NICM has important clinical value. This study is aimed to explore the predicting factors for ICM and NICM. METHODS: 1082 HFrEF patients were retrospectively enrolled from Jan. 01, 2016 to...

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Autores principales: Zhang, Zhi-hua, Meng, Fan-qi, Hou, Xiao-feng, Qian, Zhi-yong, Wang, Yao, Qiu, Yuan-hao, Jiang, Zhe-yu, Du, An-jie, Qin, Chao-tong, Zou, Jian-gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296233/
https://www.ncbi.nlm.nih.gov/pubmed/32534695
http://dx.doi.org/10.1016/j.ihj.2020.04.004
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author Zhang, Zhi-hua
Meng, Fan-qi
Hou, Xiao-feng
Qian, Zhi-yong
Wang, Yao
Qiu, Yuan-hao
Jiang, Zhe-yu
Du, An-jie
Qin, Chao-tong
Zou, Jian-gang
author_facet Zhang, Zhi-hua
Meng, Fan-qi
Hou, Xiao-feng
Qian, Zhi-yong
Wang, Yao
Qiu, Yuan-hao
Jiang, Zhe-yu
Du, An-jie
Qin, Chao-tong
Zou, Jian-gang
author_sort Zhang, Zhi-hua
collection PubMed
description OBJECTIVES: The different etiology of HF has different prognostic risk factors. Prognosis assessment of ICM and NICM has important clinical value. This study is aimed to explore the predicting factors for ICM and NICM. METHODS: 1082 HFrEF patients were retrospectively enrolled from Jan. 01, 2016 to Dec. 31, 2017. On Jan. 31, 2019, 873 patients were enrolled for analysis excluding incomplete, unfollowed, and unexplained data. The patients were divided into ischemic and non-ischemic group. The differences in clinical characteristics and long-term prognosis between the two groups were analyzed, and multivariate Cox analysis was used to predict the respective all-cause mortality, SCD and rehospitalization of CHF. RESULTS: 873 patients aged 64(53,73) were divided into two groups: ICM (403, 46.16%) and NICM. At the end, 203 died (111 in ICM, 54.68%), of whom 87 had SCD (53 in ICM, 60.92%) and 269 had rehospitalization for HF(134 in ICM, 49.81%). Independent risk factors affecting all-cause mortality in ICM: DM, previous hospitalization of HF, age, eGFR, LVEF; for SCD: PVB, eGFR, Hb, revascularization; for readmission of HF: low T3 syndrome, PVB, DM, previous hospitalization of HF, eGFR. Otherwise; factors affecting all-cause mortality in NICM: NYHA III-IV, paroxysmal AF/AFL, previous hospitalization of HF, β-blocker; for SCD: low T3 syndrome, PVB, nitrates, sodium, β-blocker; for rehospitalization of HF: paroxysmal AF/AFL, previous admission of HF, LVEF. CONCLUSIONS: Both all-cause mortality and SCD in ICM is higher than that in NICM. Different etiologies of CHF have different risk factors affecting the prognosis.
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spelling pubmed-72962332020-09-15 Clinical characteristics and long-term prognosis of ischemic and non-ischemic cardiomyopathy Zhang, Zhi-hua Meng, Fan-qi Hou, Xiao-feng Qian, Zhi-yong Wang, Yao Qiu, Yuan-hao Jiang, Zhe-yu Du, An-jie Qin, Chao-tong Zou, Jian-gang Indian Heart J Original Article OBJECTIVES: The different etiology of HF has different prognostic risk factors. Prognosis assessment of ICM and NICM has important clinical value. This study is aimed to explore the predicting factors for ICM and NICM. METHODS: 1082 HFrEF patients were retrospectively enrolled from Jan. 01, 2016 to Dec. 31, 2017. On Jan. 31, 2019, 873 patients were enrolled for analysis excluding incomplete, unfollowed, and unexplained data. The patients were divided into ischemic and non-ischemic group. The differences in clinical characteristics and long-term prognosis between the two groups were analyzed, and multivariate Cox analysis was used to predict the respective all-cause mortality, SCD and rehospitalization of CHF. RESULTS: 873 patients aged 64(53,73) were divided into two groups: ICM (403, 46.16%) and NICM. At the end, 203 died (111 in ICM, 54.68%), of whom 87 had SCD (53 in ICM, 60.92%) and 269 had rehospitalization for HF(134 in ICM, 49.81%). Independent risk factors affecting all-cause mortality in ICM: DM, previous hospitalization of HF, age, eGFR, LVEF; for SCD: PVB, eGFR, Hb, revascularization; for readmission of HF: low T3 syndrome, PVB, DM, previous hospitalization of HF, eGFR. Otherwise; factors affecting all-cause mortality in NICM: NYHA III-IV, paroxysmal AF/AFL, previous hospitalization of HF, β-blocker; for SCD: low T3 syndrome, PVB, nitrates, sodium, β-blocker; for rehospitalization of HF: paroxysmal AF/AFL, previous admission of HF, LVEF. CONCLUSIONS: Both all-cause mortality and SCD in ICM is higher than that in NICM. Different etiologies of CHF have different risk factors affecting the prognosis. Elsevier 2020 2020-04-28 /pmc/articles/PMC7296233/ /pubmed/32534695 http://dx.doi.org/10.1016/j.ihj.2020.04.004 Text en © 2020 Published by Elsevier B.V. on behalf of Cardiological Society of India. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Original Article
Zhang, Zhi-hua
Meng, Fan-qi
Hou, Xiao-feng
Qian, Zhi-yong
Wang, Yao
Qiu, Yuan-hao
Jiang, Zhe-yu
Du, An-jie
Qin, Chao-tong
Zou, Jian-gang
Clinical characteristics and long-term prognosis of ischemic and non-ischemic cardiomyopathy
title Clinical characteristics and long-term prognosis of ischemic and non-ischemic cardiomyopathy
title_full Clinical characteristics and long-term prognosis of ischemic and non-ischemic cardiomyopathy
title_fullStr Clinical characteristics and long-term prognosis of ischemic and non-ischemic cardiomyopathy
title_full_unstemmed Clinical characteristics and long-term prognosis of ischemic and non-ischemic cardiomyopathy
title_short Clinical characteristics and long-term prognosis of ischemic and non-ischemic cardiomyopathy
title_sort clinical characteristics and long-term prognosis of ischemic and non-ischemic cardiomyopathy
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296233/
https://www.ncbi.nlm.nih.gov/pubmed/32534695
http://dx.doi.org/10.1016/j.ihj.2020.04.004
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