Cargando…

Raloxifene improves TNF-α-induced osteogenic differentiation inhibition of bone marrow mesenchymal stem cells and alleviates osteoporosis

Effect of raloxifene (RLF) on the improvement of inhibited osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs) resulted from tumor necrosis factor-α (TNF-α) induction, thus alleviating the progression of osteoporosis (OP), was investigated. An in vivo OP rat model was constructe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Fenghe, Jia, Yusong, Sun, Qi, Zheng, Chenying, Liu, Chuyin, Wang, Wei, Du, Li, Kang, Shengqian, Niu, Xufeng, Li, Jinyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2020
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296296/ https://www.ncbi.nlm.nih.gov/pubmed/32550885 http://dx.doi.org/10.3892/etm.2020.8689

Ejemplares similares

Comparison of intravenous, topical or combined routes of tranexamic acid administration in patients undergoing total knee and hip arthroplasty: a meta-analysis of randomised controlled trials
por: Sun, Qi, et al.
Publicado: (2019)

Pharmacogenomics Study for Raloxifene in Postmenopausal Female with Osteoporosis
por: Lu, Hsing-Fang, et al.
Publicado: (2020)

Circular RNA Circ_0005564 promotes osteogenic differentiation of bone marrow mesenchymal cells in osteoporosis
por: Liu, Zitao, et al.
Publicado: (2021)

Alpinetin alleviates osteoporosis by promoting osteogenic differentiation in BMSCs by triggering autophagy via PKA/mTOR/ULK1 signaling
por: Zeng, Chenying, et al.
Publicado: (2022)

Applying vibration in early postmenopausal osteoporosis promotes osteogenic differentiation of bone marrow-derived mesenchymal stem cells and suppresses postmenopausal osteoporosis progression
por: Li, Huiming, et al.
Publicado: (2019)

Melatonin restores osteoporosis-impaired osteogenic potential of bone marrow mesenchymal stem cells and alleviates bone loss through the HGF/PTEN/Wnt/β-catenin axis
por: Zhang, Jun, et al.
Publicado: (2021)

Effect of aerobic exercise and raloxifene combination therapy on senile osteoporosis
por: Zhao, Chengjin, et al.
Publicado: (2016)

Combination Therapy of Raloxifene and Alendronate for Treatment of Osteoporosis in Elderly Women
por: Um, Mi Jung, et al.
Publicado: (2017)

Comparative safety and effectiveness of alendronate versus raloxifene in women with osteoporosis
por: Kim, Yeesuk, et al.
Publicado: (2020)

TNF-α-Induced SOX5 Upregulation Is Involved in the Osteogenic Differentiation of Human Bone Marrow Mesenchymal Stem Cells Through KLF4 Signal Pathway
por: Xu, Lijun, et al.
Publicado: (2018)

Design of a transdermal formulation containing raloxifene nanoparticles for osteoporosis treatment
por: Nagai, Noriaki, et al.
Publicado: (2018)

Long-term safety and efficacy of raloxifene in the prevention and treatment of postmenopausal osteoporosis: an update
por: Messalli, Enrico M, et al.
Publicado: (2010)

Effects of minodronate in postmenopausal women with osteoporosis who received prior treatment with raloxifene
por: Toda, Aska, et al.
Publicado: (2017)

Systematic review of raloxifene in postmenopausal Japanese women with osteoporosis or low bone mass (osteopenia)
por: Fujiwara, Saeko, et al.
Publicado: (2014)

Investigation of the treatment potential of Raloxifene-loaded polymeric nanoparticles in osteoporosis: In-vitro and in-vivo analyses
por: Guo, Zhonghua, et al.
Publicado: (2023)

Glucocorticoid-Induced Leucine Zipper (GILZ) Antagonizes TNF-α Inhibition of Mesenchymal Stem Cell Osteogenic Differentiation
por: He, Linlin, et al.
Publicado: (2012)

Managing the risk of invasive breast cancer in women at risk for breast cancer and osteoporosis: the role of raloxifene
por: Vogel, Victor G
Publicado: (2008)

Combined treatment with dexamethasone and raloxifene totally abrogates osteoporosis and joint destruction in experimental postmenopausal arthritis
por: Islander, Ulrika, et al.
Publicado: (2011)

Cost-effectiveness of raloxifene in the treatment of osteoporosis in Chinese postmenopausal women: impact of medication persistence and adherence
por: Chen, Mingsheng, et al.
Publicado: (2016)

A Nationwide Study on the Incidence of Breast Cancer in Korean Women with Osteoporosis Receiving Raloxifene Treatment
por: Lee, Jihyoun, et al.
Publicado: (2021)

Raloxifene in Hemodialysis Patients
por: Keller, Frieder
Publicado: (2012)

Oxidative Stress and Raloxifene
por: Akgol, Gurkan, et al.
Publicado: (2012)

Impact of bone marrow mesenchymal stem cell immunomodulation on the osteogenic effects of laponite
por: Li, Tao, et al.
Publicado: (2018)

Roles for miRNAs in osteogenic differentiation of bone marrow mesenchymal stem cells
por: Wang, Jicheng, et al.
Publicado: (2019)

Long non-coding RNA taurine upregulated gene 1 is downregulated in osteoporosis and influences the osteogenic differentiation of bone marrow mesenchymal stem cells
por: Teng, Zhaowei, et al.
Publicado: (2021)

Research progress on the role of lncRNA–miRNA networks in regulating adipogenic and osteogenic differentiation of bone marrow mesenchymal stem cells in osteoporosis
por: An, Fangyu, et al.
Publicado: (2023)

Raloxifene/Vitamin D Combination Therapy vs. Raloxifene Monotherapy on Serum 25-Hydroxy-Vitamin D Level among Postmenopausal Women with Osteoporosis or Osteopenia: A Randomized Controlled Trial
por: Lee, You-Bin, et al.
Publicado: (2022)

Effects of zearalenone and α-Zearalenol in comparison with Raloxifene on T47D cells
por: Khosrokhavar, Roya, et al.
Publicado: (2009)

Uncarboxylated osteocalcin alleviates the inhibitory effect of high glucose on osteogenic differentiation of mouse bone marrow–derived mesenchymal stem cells by regulating TP63
por: Gong, Fangzi, et al.
Publicado: (2021)

Extracellular Vesicles Derived from Osteogenic-Differentiated Human Bone Marrow-Derived Mesenchymal Cells Rescue Osteogenic Ability of Bone Marrow-Derived Mesenchymal Cells Impaired by Hypoxia
por: Wang, Chenglong, et al.
Publicado: (2023)

Reactive oxygen species mediate TNF-α-induced inflammatory response in bone marrow mesenchymal cells
por: Wu, Liuzhong, et al.
Publicado: (2019)

Osteogenic effects of rapamycin on bone marrow mesenchymal stem cells via inducing autophagy
por: Xing, Yifeng, et al.
Publicado: (2023)

Safety of Raloxifene in Hemodialysis Patients
por: Jacobsen, Didy
Publicado: (2012)

Influence of glucocorticoids on the osteogenic differentiation of rat bone marrow-derived mesenchymal stem cells
por: Zhou, Da-An, et al.
Publicado: (2014)

Mechanical Strain Regulates Osteogenic and Adipogenic Differentiation of Bone Marrow Mesenchymal Stem Cells
por: Li, Runguang, et al.
Publicado: (2015)

CCK regulates osteogenic differentiation through TNFα/NF-κB in peri-implantitis
por: Chou, LongHang, et al.
Publicado: (2022)

Abnormal Cell Responses and Role of TNF-α in Impaired Diabetic Wound Healing
por: Xu, Fanxing, et al.
Publicado: (2013)

Mangiferin promotes osteogenic differentiation and alleviates osteoporosis in the ovariectomized mouse via the AXL/ERK5 pathway
por: He, Jinwen, et al.
Publicado: (2022)

Co‐consuming green tea with raloxifene decreases raloxifene systemic exposure in healthy adult participants
por: Clarke, John D., et al.
Publicado: (2023)

BMPRIA is required for osteogenic differentiation and RANKL expression in adult bone marrow mesenchymal stromal cells
por: Biswas, Soma, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_h38k9lup8jtb25um41n1ktv0je