Isolated central nervous system relapse of multiple myeloma post autologous stem cell transplant- A rare presentation

• CNS relapse in multiple myeloma after ASCT without medullary relapse is uncommon. • Isolated CNS relapse is extremely rare with only 7 cases reported in literature. • Prognosis is poor with very short median survival after detection of CNS relapse. • Management is based on IMiD's and intrathe...

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Detalles Bibliográficos
Autores principales: Mittal, Abhenil, Pushpam, Deepam, Kumar, Lalit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296331/
https://www.ncbi.nlm.nih.gov/pubmed/32566478
http://dx.doi.org/10.1016/j.lrr.2020.100207
Descripción
Sumario:• CNS relapse in multiple myeloma after ASCT without medullary relapse is uncommon. • Isolated CNS relapse is extremely rare with only 7 cases reported in literature. • Prognosis is poor with very short median survival after detection of CNS relapse. • Management is based on IMiD's and intrathecal therapy with radiation.

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