Cargando…

Isolated central nervous system relapse of multiple myeloma post autologous stem cell transplant- A rare presentation

• CNS relapse in multiple myeloma after ASCT without medullary relapse is uncommon. • Isolated CNS relapse is extremely rare with only 7 cases reported in literature. • Prognosis is poor with very short median survival after detection of CNS relapse. • Management is based on IMiD's and intrathe...

Descripción completa

Detalles Bibliográficos
Autores principales: Mittal, Abhenil, Pushpam, Deepam, Kumar, Lalit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296331/
https://www.ncbi.nlm.nih.gov/pubmed/32566478
http://dx.doi.org/10.1016/j.lrr.2020.100207
_version_ 1783546828201918464
author Mittal, Abhenil
Pushpam, Deepam
Kumar, Lalit
author_facet Mittal, Abhenil
Pushpam, Deepam
Kumar, Lalit
author_sort Mittal, Abhenil
collection PubMed
description • CNS relapse in multiple myeloma after ASCT without medullary relapse is uncommon. • Isolated CNS relapse is extremely rare with only 7 cases reported in literature. • Prognosis is poor with very short median survival after detection of CNS relapse. • Management is based on IMiD's and intrathecal therapy with radiation.
format Online
Article
Text
id pubmed-7296331
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-72963312020-06-18 Isolated central nervous system relapse of multiple myeloma post autologous stem cell transplant- A rare presentation Mittal, Abhenil Pushpam, Deepam Kumar, Lalit Leuk Res Rep Article • CNS relapse in multiple myeloma after ASCT without medullary relapse is uncommon. • Isolated CNS relapse is extremely rare with only 7 cases reported in literature. • Prognosis is poor with very short median survival after detection of CNS relapse. • Management is based on IMiD's and intrathecal therapy with radiation. Elsevier 2020-06-08 /pmc/articles/PMC7296331/ /pubmed/32566478 http://dx.doi.org/10.1016/j.lrr.2020.100207 Text en © 2020 Published by Elsevier Ltd. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Mittal, Abhenil
Pushpam, Deepam
Kumar, Lalit
Isolated central nervous system relapse of multiple myeloma post autologous stem cell transplant- A rare presentation
title Isolated central nervous system relapse of multiple myeloma post autologous stem cell transplant- A rare presentation
title_full Isolated central nervous system relapse of multiple myeloma post autologous stem cell transplant- A rare presentation
title_fullStr Isolated central nervous system relapse of multiple myeloma post autologous stem cell transplant- A rare presentation
title_full_unstemmed Isolated central nervous system relapse of multiple myeloma post autologous stem cell transplant- A rare presentation
title_short Isolated central nervous system relapse of multiple myeloma post autologous stem cell transplant- A rare presentation
title_sort isolated central nervous system relapse of multiple myeloma post autologous stem cell transplant- a rare presentation
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296331/
https://www.ncbi.nlm.nih.gov/pubmed/32566478
http://dx.doi.org/10.1016/j.lrr.2020.100207
work_keys_str_mv AT mittalabhenil isolatedcentralnervoussystemrelapseofmultiplemyelomapostautologousstemcelltransplantararepresentation
AT pushpamdeepam isolatedcentralnervoussystemrelapseofmultiplemyelomapostautologousstemcelltransplantararepresentation
AT kumarlalit isolatedcentralnervoussystemrelapseofmultiplemyelomapostautologousstemcelltransplantararepresentation