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Isolated central nervous system relapse of multiple myeloma post autologous stem cell transplant- A rare presentation
• CNS relapse in multiple myeloma after ASCT without medullary relapse is uncommon. • Isolated CNS relapse is extremely rare with only 7 cases reported in literature. • Prognosis is poor with very short median survival after detection of CNS relapse. • Management is based on IMiD's and intrathe...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296331/ https://www.ncbi.nlm.nih.gov/pubmed/32566478 http://dx.doi.org/10.1016/j.lrr.2020.100207 |
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author | Mittal, Abhenil Pushpam, Deepam Kumar, Lalit |
author_facet | Mittal, Abhenil Pushpam, Deepam Kumar, Lalit |
author_sort | Mittal, Abhenil |
collection | PubMed |
description | • CNS relapse in multiple myeloma after ASCT without medullary relapse is uncommon. • Isolated CNS relapse is extremely rare with only 7 cases reported in literature. • Prognosis is poor with very short median survival after detection of CNS relapse. • Management is based on IMiD's and intrathecal therapy with radiation. |
format | Online Article Text |
id | pubmed-7296331 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-72963312020-06-18 Isolated central nervous system relapse of multiple myeloma post autologous stem cell transplant- A rare presentation Mittal, Abhenil Pushpam, Deepam Kumar, Lalit Leuk Res Rep Article • CNS relapse in multiple myeloma after ASCT without medullary relapse is uncommon. • Isolated CNS relapse is extremely rare with only 7 cases reported in literature. • Prognosis is poor with very short median survival after detection of CNS relapse. • Management is based on IMiD's and intrathecal therapy with radiation. Elsevier 2020-06-08 /pmc/articles/PMC7296331/ /pubmed/32566478 http://dx.doi.org/10.1016/j.lrr.2020.100207 Text en © 2020 Published by Elsevier Ltd. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Article Mittal, Abhenil Pushpam, Deepam Kumar, Lalit Isolated central nervous system relapse of multiple myeloma post autologous stem cell transplant- A rare presentation |
title | Isolated central nervous system relapse of multiple myeloma post autologous stem cell transplant- A rare presentation |
title_full | Isolated central nervous system relapse of multiple myeloma post autologous stem cell transplant- A rare presentation |
title_fullStr | Isolated central nervous system relapse of multiple myeloma post autologous stem cell transplant- A rare presentation |
title_full_unstemmed | Isolated central nervous system relapse of multiple myeloma post autologous stem cell transplant- A rare presentation |
title_short | Isolated central nervous system relapse of multiple myeloma post autologous stem cell transplant- A rare presentation |
title_sort | isolated central nervous system relapse of multiple myeloma post autologous stem cell transplant- a rare presentation |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296331/ https://www.ncbi.nlm.nih.gov/pubmed/32566478 http://dx.doi.org/10.1016/j.lrr.2020.100207 |
work_keys_str_mv | AT mittalabhenil isolatedcentralnervoussystemrelapseofmultiplemyelomapostautologousstemcelltransplantararepresentation AT pushpamdeepam isolatedcentralnervoussystemrelapseofmultiplemyelomapostautologousstemcelltransplantararepresentation AT kumarlalit isolatedcentralnervoussystemrelapseofmultiplemyelomapostautologousstemcelltransplantararepresentation |