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Variable Outcomes in Neural Differentiation of Human PSCs Arise from Intrinsic Differences in Developmental Signaling Pathways

Directed differentiation of human pluripotent stem cells varies in specificity and efficiency. Stochastic, genetic, intracellular, and environmental factors affect maintenance of pluripotency and differentiation into early embryonic lineages. However, factors affecting variation in in vitro differen...

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Detalles Bibliográficos
Autores principales:	Strano, Alessio, Tuck, Eleanor, Stubbs, Victoria E., Livesey, Frederick J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296348/ https://www.ncbi.nlm.nih.gov/pubmed/32521257 http://dx.doi.org/10.1016/j.celrep.2020.107732

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