Cargando…

Uncontrolled Acute Intermittent Porphyria as a Cause of Spontaneous Abortion

INTRODUCTION: The association of acute intermitetn porphyria (AIP) with pregnancy and as a cause of spontaneous abortion is rare. AIM: To show a case of AIP known before pregnancy in a patient who had a spontaneous abortion. CASE REPORT: A gynecologist examined 26-year-old patient in the 8th week of...

Descripción completa

Detalles Bibliográficos
Autores principales: Cerovac, Anis, Brigic, Alma, Softic, Dzenana, Barakovic, Amna, Adzajlic, Semir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academy of Medical Sciences of Bosnia and Herzegovina 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296395/
https://www.ncbi.nlm.nih.gov/pubmed/32577061
http://dx.doi.org/10.5455/medarh.2020.74.153-155
_version_ 1783546837351792640
author Cerovac, Anis
Brigic, Alma
Softic, Dzenana
Barakovic, Amna
Adzajlic, Semir
author_facet Cerovac, Anis
Brigic, Alma
Softic, Dzenana
Barakovic, Amna
Adzajlic, Semir
author_sort Cerovac, Anis
collection PubMed
description INTRODUCTION: The association of acute intermitetn porphyria (AIP) with pregnancy and as a cause of spontaneous abortion is rare. AIM: To show a case of AIP known before pregnancy in a patient who had a spontaneous abortion. CASE REPORT: A gynecologist examined 26-year-old patient in the 8th week of gestation, due to initial spontaneous abortion, abdominal pain, constipation, muscle weakness, vomiting and dark colour of urine. Her therapy was dydrogesterone. In consultation with an anesthesiologist, a short intravenous anesthesia, vacuum aspiration, and curettage were performed.During hospitalization, the patient ceased to take harmful drugs and she was given haemarginate, glucose and symptomatic drugs, and she recovered completely. CONCLUSION: Treatment of threatened spontaneous abortion in AIP remains the subject of dilemma and controversy, and future research is needed.
format Online
Article
Text
id pubmed-7296395
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Academy of Medical Sciences of Bosnia and Herzegovina
record_format MEDLINE/PubMed
spelling pubmed-72963952020-06-22 Uncontrolled Acute Intermittent Porphyria as a Cause of Spontaneous Abortion Cerovac, Anis Brigic, Alma Softic, Dzenana Barakovic, Amna Adzajlic, Semir Med Arch Case Report INTRODUCTION: The association of acute intermitetn porphyria (AIP) with pregnancy and as a cause of spontaneous abortion is rare. AIM: To show a case of AIP known before pregnancy in a patient who had a spontaneous abortion. CASE REPORT: A gynecologist examined 26-year-old patient in the 8th week of gestation, due to initial spontaneous abortion, abdominal pain, constipation, muscle weakness, vomiting and dark colour of urine. Her therapy was dydrogesterone. In consultation with an anesthesiologist, a short intravenous anesthesia, vacuum aspiration, and curettage were performed.During hospitalization, the patient ceased to take harmful drugs and she was given haemarginate, glucose and symptomatic drugs, and she recovered completely. CONCLUSION: Treatment of threatened spontaneous abortion in AIP remains the subject of dilemma and controversy, and future research is needed. Academy of Medical Sciences of Bosnia and Herzegovina 2020-04 /pmc/articles/PMC7296395/ /pubmed/32577061 http://dx.doi.org/10.5455/medarh.2020.74.153-155 Text en © 2020 Anis Cerovac, Alma Brigic, Dzenana Softic, Amna Barakovic, Semir Adzajlic http://creativecommons.org/licenses/by-nc/4.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Cerovac, Anis
Brigic, Alma
Softic, Dzenana
Barakovic, Amna
Adzajlic, Semir
Uncontrolled Acute Intermittent Porphyria as a Cause of Spontaneous Abortion
title Uncontrolled Acute Intermittent Porphyria as a Cause of Spontaneous Abortion
title_full Uncontrolled Acute Intermittent Porphyria as a Cause of Spontaneous Abortion
title_fullStr Uncontrolled Acute Intermittent Porphyria as a Cause of Spontaneous Abortion
title_full_unstemmed Uncontrolled Acute Intermittent Porphyria as a Cause of Spontaneous Abortion
title_short Uncontrolled Acute Intermittent Porphyria as a Cause of Spontaneous Abortion
title_sort uncontrolled acute intermittent porphyria as a cause of spontaneous abortion
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296395/
https://www.ncbi.nlm.nih.gov/pubmed/32577061
http://dx.doi.org/10.5455/medarh.2020.74.153-155
work_keys_str_mv AT cerovacanis uncontrolledacuteintermittentporphyriaasacauseofspontaneousabortion
AT brigicalma uncontrolledacuteintermittentporphyriaasacauseofspontaneousabortion
AT softicdzenana uncontrolledacuteintermittentporphyriaasacauseofspontaneousabortion
AT barakovicamna uncontrolledacuteintermittentporphyriaasacauseofspontaneousabortion
AT adzajlicsemir uncontrolledacuteintermittentporphyriaasacauseofspontaneousabortion