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Removal of H2Aub1 by ubiquitin-specific proteases 12 and 13 is required for stable Polycomb-mediated gene repression in Arabidopsis

BACKGROUND: Stable gene repression is essential for normal growth and development. Polycomb repressive complexes 1 and 2 (PRC1&2) are involved in this process by establishing monoubiquitination of histone 2A (H2Aub1) and subsequent trimethylation of lysine 27 of histone 3 (H3K27me3). Previous wo...

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Detalles Bibliográficos
Autores principales:	Kralemann, Lejon E. M., Liu, Shujing, Trejo-Arellano, Minerva S., Muñoz-Viana, Rafael, Köhler, Claudia, Hennig, Lars
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296913/ https://www.ncbi.nlm.nih.gov/pubmed/32546254 http://dx.doi.org/10.1186/s13059-020-02062-8

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